1. Overview
Diphenyl Acetonitrile, also known as 2,2-Diphenylacetonitrile, is an important organic intermediate widely used in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. Its unique molecular structure - a nitrile group connected to a diphenyl moiety - makes it a versatile building block in organic synthesis.
2. Chemical Information
CAS Number: 86-29-3
Molecular Formula: C14H11N
Molecular Weight: 193.24 g/mol
Appearance: White to off-white crystalline powder
Purity: Typically ≥ 98% for industrial applications
3. Key Applications
Pharmaceutical Intermediates: Used in the synthesis of antihistamines, anti-inflammatory drugs, and other active pharmaceutical ingredients (APIs).
Agrochemicals: Precursor in manufacturing certain herbicides, fungicides, and insecticides.
Specialty Chemicals: Applied in fragrance synthesis, dyes, and advanced materials.
Organic Synthesis: Functions as a building block for creating benzyl derivatives and heterocyclic compounds.
4. Production and Supply
Industrial production of Diphenyl Acetonitrile often involves the dehydration of corresponding amides or catalytic processes starting from diphenylacetic acid derivatives. Leading suppliers provide it in various grades, ensuring consistent purity and stability for both lab and bulk-scale manufacturing.
5. Safety and Handling
Hazards: May cause skin and eye irritation; harmful if inhaled or ingested.
Storage: Store in a cool, dry, and well-ventilated area, away from strong oxidizing agents.
Protective Measures: Use gloves, goggles, and appropriate respiratory protection during handling.
6. Market Outlook
Driven by growth in the pharmaceutical and agrochemical sectors, the demand for high-purity Diphenyl Acetonitrile is expected to rise steadily. Asia-Pacific, particularly China and India, remains a major production hub, while Europe and North America lead in specialty applications.
7. Conclusion
Diphenyl Acetonitrile (CAS 86-29-3) is an essential intermediate with broad industrial value. Choosing a reliable supplier with stringent quality control is critical for achieving consistent performance in downstream applications.
