Your Professional Extracts Manufacturer!
 

Located in Xiasha Economic Development Park of Hangzhou city (capital of Zhejiang province in the southeast coastal region of China), Hangzhou Dingyan Chem Co.,Ltd is a modern private enterprise; The company was founded in 2013 and has more than ten years of experience in this industry. we are mainly engaged in the development, trade and independent import and export business of hi-tech products such as pharmaceutical materials (APIs), pharmaceutical intermediates, fine chemicals and biochemical reagents, etc.

 

 
  • Gibberellic Acid CAS 77-06-5
    Product Name: Gibberellic acidCAS No.: 77-06-5Molecular Formula: C19H22O6Molecular Weight: 346.38Melting Point: 227 °CSpecific Rotation: 82.5 º (c=10, ethanol)Boiling Point: 401.12°C (rough
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  • 6-Benzylaminopurine CAS 1214-39-7
    Product Name: 6-BenzylaminopurineCAS No.: 1214-39-7Molecular Formula: C12H11N5Molecular Weight: 225.25Melting Point: 230-233 °CBoiling Point: 145 °C (lit.)Density: 0.899 g/mL at 20 °CVapor Density:
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  • Kinetin CAS 525-79-1
    Product Name: KinetinCAS No.: 525-79-1Molecular Formula: C10H9N5OMolecular Weight: 215.21Melting Point: 269-271 °C (dec.)(lit.)Boiling Point: 355.49 °C (rough estimate)Bulk Density: 360 kg/m³Density:
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  • Indole-3-butyric Acid CAS 133-32-4
    Product Name: Indole-3-butyric acidCAS No.: 133-32-4Molecular Formula: C12H13NO2Molecular Weight: 203.24Melting Point: 124-125.5 °C (lit.)Boiling Point: 341.55 °C (rough estimate)Bulk Density: 360
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  • Abscisic Acid CAS 14375-45-2
    Product Name: Abscisic acidCAS No.: 14375-45-2Molecular Formula: C15H20O4Molecular Weight: 264.32Melting Point: 186-188 °C (lit.)Boiling Point: 458.7±45.0 °C (Predicted)Density: 1.193±0.06 g/cm3
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  • MORIN CAS 480-16-0
    Product Name: MORINCAS No.: 480-16-0Molecular Formula: C15H10O7Molecular Weight: 302.24Melting Point: 299-300 °C (dec.)(lit.)Boiling Point: 363.28 °C (rough estimate)Density: 1.3616 (rough
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  • Eucalyptus Oil CAS 8000-48-4
    Product Name: Eucalyptus oilCAS No.: 8000-48-4Molecular Formula: C10H18OMolecular Weight: 154.25Boiling Point: 200 °CDensity: 0.909 g/mL at 25 °CFEMA2466 | EUCALYPTUS OIL (EUCALYPTUS GLOBULUS
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  • Cineole CAS 470-82-6
    Product Name: CineoleCAS No.: 470-82-6Molecular Formula: C10H18OMolecular Weight: 154.25Melting Point: 1-2 °C (lit.)Boiling Point: 176-177 °C (lit.)Density: 0.9225Vapor Pressure: 1.22 hPa at 20
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  • 18β-Glycyrrhetinic Acid CAS 471-53-4
    Product Name: 18β-Glycyrrhetinic AcidCAS No.: 471-53-4Molecular Formula: C30H46O4Molecular Weight: 470.69Melting Point: 292-295 °C (lit.)Specific Rotation: 165 ° (c=1, CHCl3, on dry ba)Boiling Point:
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  • Puerarin CAS 3681-99-0
    Product Name: PuerarinCAS No.: 3681-99-0Molecular Formula: C21H20O9Molecular Weight: 416.38Melting Point: 187-189°CBoiling Point: 688.0±55.0 °C (Predicted)Density: 1.614±0.06 g/cm3
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  • Esculin CAS 531-75-9
    Product Name: EsculinCAS No.: 531-75-9Molecular Formula: C15H16O9Molecular Weight: 340.28Melting Point: 203 °CSpecific Rotation: -88 °C (c=2, dioxane/water 1:1)Boiling Point: 396.1 °C (rough
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  • Apigenin CAS 520-36-5
    Product Name: ApigeninCAS No.: 520-36-5Molecular Formula: C15H10O5Molecular Weight: 270.24Melting Point: >300 °C (lit.)Boiling Point: 333.35 °C (rough estimate)Density: 1.2319 (rough
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Why Choose Us

Rich Experience

The company was founded in 2013 and has more than ten years of experience in this industry.

High Quality

Our products are manufactured or executed to very high standards, using the finest materials and manufacturing processes.

Research And Development

Insisting on the development path of "scientific and technological innovation" since our foundation, dingyan-chemical has laid great stresses on the research and development of scientific and technological innovation.

 

Production Market

Dingyan's products are well sold in more than 60 countries and regions in North America, Western Europe, Southeast Asia, Central and South America, and then established long-term and steady relations of cooperation with many pharmaceutical enterprises in Europe, USA, Greece, Germany, South Korea and India, etc.

 

Types Of Extracts

 

The extracts produced by our company mainly include the following types:
D-mannitol 69-65-8
D-Mannitol is a hexavalent alcohol widely distributed in plants and plant secretions. It can be extracted from kelp or seaweed and is also obtained through the catalytic hydrogenation of glucose or sucrose. Natural products containing mannitol are commonly found in the leaves, stems, roots, and other parts of plants. For example, the white powder on the surface of seaweed and dried persimmons is mannitol. It is also present in high concentrations in edible fungi, lichens, onions, and carrots. The mannan obtained from the sap (secretions, dried) of Fraxinus ornus, a plant in the Oleaceae family, contains 30% to 50% mannitol.

 

Items

Standard

Appearance

White crystalline, powder; taste, sweetish

Identification(1)

It should be dark pink

Identification(2)

It should be consistent with the main peak retention time of the standard solution chromatogram

Loss 0n Drying %

≤0.3

D-mannitol content (on dry basis)%

96.0-101.5

PH(100g/L)(PH Value)

4.0-7.5

Reducing Sugar %

≤0.3

Residue On Ignition)%

≤0.1

Lead mg/kg

≤1.0

Nickel mg/kg

≤1.0

 

Betulinic Acid 472-15-1
Betulinic acid is a pentacyclic triterpene compound that is widely found in nature. It was first isolated from the bark of evergreen plants of the Rhamnaceae family growing in Eastern Africa, but its main source is the bark of birch trees, from which it is extracted and purified. Recent scientific research has shown that betulinic acid (BA) is a very valuable natural product. BA and its derivatives have demonstrated significant potential as biological agents in the treatment of cancer and HIV. They play an important role in protecting the body from oxidative damage and in immune regulation. These compounds are considered highly promising drug leads and hold great potential for the development of new medicines. The U.S. National Cancer Institute (NCI) has included them in its Rapid Access to Interventional Development (RAID) program.

 

Items

Standard

Appearance

Off-white to White fine powder

Identification

Positive

Loss on Drying

≤5.0%

Ashes

≤2.0%

Purity(by HPLC)

≥98%

Solvent Residue

≤5000ppm

Heavy Metals

≤10ppm

Lead

≤2ppm

Arsenic

≤1ppm

Mercury

≤0.1ppm

Cadmium

≤1ppm

Microbiological

Total Plate Count

<1000cfu/g

Yeast& Mold

<100cfu/g

E.Coli

Negative

Salmonella

Negative

Staphylococcus

Negative

 

Advantages of Extracts

 

D-Mannitol 69-65-8

Advantages of D-mannitol 69-65-8

 

 

Low Caloric Value

D-Mannitol contains fewer calories than regular sugar, making it an ideal choice for low-calorie products.

Non-Cariogenic

Unlike sugars, D-Mannitol does not contribute to tooth decay, making it safer for dental health.

Versatile Usage

Easily incorporated into various manufacturing processes across industries.

Stability

Exhibits high stability under different temperatures and environments, which is vital for product formulation.

Enhanced Solubility

Improves solubility for many active pharmaceutical ingredients, ensuring better absorption and efficacy.

 

Advantages of Betulinic Acid 472-15-1
 

Anti-cancer properties
Some cancer therapies containing betulinic acids have shown effectiveness against brain tumors like glioblastoma. These compounds can potentially induce apoptosis or programmed cell death in malignant cells. They also disrupt cancer cell's ability to multiply and grow. This makes them useful in combating several types of cancers, including breast, prostate, and colon cancers.

 

Antiviral activity
Betulinic acid has proved effective in combating certain viruses. These include the herpes simplex virus and the cytomegalovirus. Its activity against HIV is particularly noteworthy. Some studies indicate that betulinic acid may help inhibit the replication of the HIV virus. This opens possibilities for using it in developing antiviral treatments.

 

Anti-inflammatory properties
Betulinic acid have anti-inflammatory effects. PHWs may treat conditions like arthritis by reducing inflammation and associated pain. They also help manage chronic inflammatory diseases, which are currently impossible to cure. These are diseases like inflammatory bowel disease (IBD) and asthma.

 

Neuroprotective effects
Betulinic acid may protect brain cells from damage, which could be beneficial in degenerative diseases. These include Alzheimer's and Parkinson's. Its ability to cross the blood-brain barrier is particularly valuable in developing treatments aimed at brain-related disorders. There is still a need for more clinical studies to fully understand its neuroprotective potential. However, early research suggests that betulinic acid could help slow or prevent the onset of neurodegenerative diseases.

 

Application of Extracts

 

Application of D-mannitol 69-65-8

 

Betulinic Acid 472-15-1

Pharmaceutical Applications

Used in formulations to improve drug solubility.
Acts as a protective agent for sensitive proteins and enzymes.
Serves as an osmotic agent in medical treatments.

2

Food Industry

Incorporated as a sweetening agent in low-calorie foods.
Used to improve texture and extend shelf life.
Acts as a bulking agent in dietary snacks and products.

1-Naphthaleneacetic Acid 86-87-3

Cosmetics and Personal Care

Used as a humectant to retain moisture in creams and lotions.
In formulations to stabilize emulsions.
Acts as a thickening agent in personal care products.

 

 
Application of Betulinic Acid 472-15-1
 
01/

Pharmaceutical Industry
Betulinic acid has anti-cancer properties and can be used to create drugs to treat and manage a variety of diseases and infections. It is particularly good at fighting cytomegalovirus and other viruses. Betulinic acid is highly regarded for its powerful anti-inflammatory, antioxidant and antimicrobial properties.

02/

Nutraceuticals and Dietary Supplements
Betulinic acid, in the form of pure compounds or concentrated extracts, is often used in dietary supplements to boost immunity, detoxify and regulate blood sugar.

03/

Cosmetics and Skin Care
Betulinic acid is widely used in cosmetics and skin care products due to its anti-inflammatory, antioxidant and antimicrobial properties. These products include skin care products for eczema, acne, psoriasis, dermatitis and anti-aging products.

04/

Food and Beverage Industry
Drinks such as tea and birch sap are popular for their detoxifying and diuretic properties, helping to promote health and hydration. Birch sap can also be harvested and made into a refreshing, slightly sweet, low-calorie beverage that is rich in vitamins and minerals to nourish and moisturize the skin.

05/

Traditional Medicine and Herbal Medicine
In traditional medicine and herbal medicine, birch bark extract has long been used for detoxification, immune support, joint and skin health, and general disease prevention and maintenance.

06/

Biotechnology and Research
Betulinic acid has been extensively studied in the biotechnology and biomedical fields for its potential anti-cancer properties and immunomodulatory effects.

 

 

Storage and transportation

 

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Our Certificates

 

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FAQ

 

Q: Can i get some samples?

A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.

Q: How to start orders or make payments?

A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, L/C , Paypal , MoneyGram or Escrow(Alibaba).

Q: How to confirm the Product Quality before placing orders?

A: You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.

Q: What's your MOQ?

A: Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Q: How about delivery leadtime?

A: Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)

Q: Is there a discount?

A: Different quantity has different discount.

Q: How do you treat quality complaint?

A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

Q: What is the difference between betulin and betulinic acid?

A: Betulin is a naturally occurring lupane-type pentacyclic triterpene, wildly distributed in plants, especially Betulinaceae. One of its derivatives, formed by oxidation, is betulinic acid.

Q: What is the benefit of betulinic acid?

A: Betulinic acid, a naturally occurring titerpene, boasts a range of potential health benefits, including anti-inflammatory, antioxidant, and anticancer properties. It's found in various plants, particularly birch bark, and has been studied for its ability to protect the skin barrier, improve skin tone, and promote overall skin health. Additionally, research suggests it may have anti-HIV, antimalarial, and anti-diabetic effects.

Q: What is the difference between mannitol and D-mannitol?

A: He key difference between mannitol and D-mannitol is that mannitol is a type of sugar useful as a sweetener and as a medication, whereas D-mannitol is the D enantiomer of mannitol which is the most abundant and useful mannitol. Mannitol is a sugar alcohol that is useful both as a sweetener and as a medication.

We're professional extracts manufacturers and suppliers in China, specialized in providing high quality customized service. If you're going to wholesale discount pharmaceutical and chemical raw materials, welcome to get free sample from our factory.

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