Retatrutide CAS 2381089-83-2

Retatrutide CAS 2381089-83-2
Details:
Product Name: Retatrutide
CAS No.: 2381089-83-2
Molecular Weight: 0 EINECS No.: 200-001-8
MDL No.:/
Solubility: Acetonitrile: Slightly soluble DMSO: Sparingly Soluble: 1-10 mg/mL
PBS (pH 7.2): Sparingly Soluble: 1-10 mg/mL
Water Solubility: Soluble in water (5 mg/mL).
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Description
Technical Parameters

 

Products Description

 

Retatrutide is a glucose-dependent insulinotropic peptide, glucagon-like peptide-1 (GLP-1), and glucagon receptor agonist. Its dose-response relationship regarding side effects, safety, and efficacy in treating obesity remains unclear.

 

 

Application

 

Retatrutide is a GLP-1 receptor agonist, a long-acting hypoglycemic agent that regulates blood sugar, slows gastric emptying, and suppresses appetite by mimicking the intestinal hormone GLP-1. It is primarily used to treat type 2 diabetes and, in some cases, as an adjunct to weight management. Its core mechanism of action involves enhancing insulin secretion, inhibiting glucagon release, and reducing food intake to achieve blood sugar control and weight loss. It should be used under the guidance of a physician. Retatrutide works by activating GLP-1 receptors, which are distributed in the pancreas, gastrointestinal tract, and brain.

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Quality Standard

Items

Standard

Appearance

White to off white powder

Solubility

Can be dissolved to 5mg/ml in pure water

Molecular Ion Mass

4731.4 ± 1.0Da

pH

7.0~9.0 (C=5mg/ml)

Water content (K.F)

NMT 8.0%

Purity (HPLC)

NLT 98.0%

Related Substances (HPLC)

The largest individual impurity test NMT 1.0%

The total impurities test NMT 2.0%

Residual Solvent (GC)

Methylene chloride

Acetonitrile

Methanol

N,N-Dimethylformamide

Tert-butyl methyl ether

Acid group ions (IC)

TFA

PO₄³⁻

HAC

Sodium ion (IC)

NMT 5.0%

Bacterial Endotoxins

NMT 10 EU/mg

Microbial Limits

TAMC

TYMC

Escherichia Coli presence

Salmonella

Aeruginosa

S. Aureus

Peptide Content (Mass Balance)

NULT 80.0%

Assay (HPLC)

95-105%(on anhydrous and salt-free substance basis)

Storage and transportation

Storage conditions:

Unopened Retaglutide should be refrigerated at **2-8℃** and should not be frozen. Retaglutide in use can be stored at room temperature not exceeding 30℃ and should be used within 4 weeks. Avoid high temperatures and light: Do not expose the medication to high temperatures or direct sunlight, as these may affect its stability and efficacy. For example, do not place the medication near a car dashboard or other areas prone to heat and light. Pay attention to the expiration date: Regularly check the expiration date of the medication. Ensure the medication is within its expiration date before use. Expired medication should be disposed of promptly and should not be used.

 

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product-480-328

Marketing

 

Our products are sold well in more than 60 countries and regions including North America, Western Europe, Southeast Asia, Central and South America, etc. We have established long-term and stable cooperative relations with pharmaceutical companies in Europe, the United States, Greece, Germany, Iran, Russia, South Korea, India and other countries.

 

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