Acetyl Chloride CAS 75-36-5

Introduction: Acetyl chloride is a colorless, fuming liquid with a strong odor and is irritating to the eyes. Its relative density is 1.1051 (20℃), melting point -112℃, boiling point 51-52℃, and flash point 4.4℃ (closed dish). It slowly decomposes in moist air, emitting white fumes, and hydrolyzes violently in water to form acetic acid and hydrogen chloride; therefore, it should be stored in a sealed container. It is miscible with benzene, acetone, chloroform, diethyl ether, glacial acetic acid, and petroleum ether. The liquid is heavier than water, and the vapor is heavier than air. It is chemically reactive and can undergo double displacement reactions with many compounds. Acetyl chloride can bind to sulfhydryl groups in proteins, therefore it is toxic to humans. It is an important acetylation reagent, with a stronger acylation ability than acetic anhydride. It is widely used in organic synthesis. It is also a catalyst for the chlorination reaction of carboxylic acids.

Applications: Acetyl chloride is a very useful synthetic intermediate. It is a derivative of the weak acid acetic acid and is used as a reagent in many industrial processes. It is a chemical used for acetylation in the synthesis or derivatization of organic compounds.

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