Meropenem Trihydrate CAS 119478-56-7

Meropenem Trihydrate CAS 119478-56-7
Details:
Product Name: Mercopenem Trihydrate
CAS No.: 119478-56-7
Molecular Formula: C17H27N3O6S
Molecular Weight: 401.48
Melting Point: >192°C (dec.)
Specific Rotation: -17~-21°C (d/20℃) (c=0.5, H2O) (calculated on the dehydrous basis)
Boiling Point: 627℃
Flash Point: >110° (230°F)
Solubility: Soluble in aqueous solution at approximately 5 mg/ml
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Description
Technical Parameters

 

Products Description

 

Meropenem Trihydrate is a synthetic broad-spectrum carbapenem antibiotic that exerts its antibacterial effect by inhibiting bacterial cell wall synthesis. Meropenem readily penetrates the cell walls of most Gram-positive and Gram-negative bacteria to reach its target, penicillin-binding proteins (PBPs).

 

 

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Application

 

Meropenem Trihydrate is indicated for adults and children for the following infections caused by single or multiple meropenem-sensitive bacteria: pneumonia (including hospital-acquired pneumonia); urinary tract infections; gynecological infections such as endometritis and pelvic inflammatory disease; skin and soft tissue infections; meningitis; and sepsis. For empirical treatment, in adults with granulocytopenia and fever, it can be used alone or in combination with antiviral or antifungal agents. Meropenem, alone or in combination with other antimicrobial agents, can be used to treat infections caused by multiple bacteria. There is currently no experience with the use of this product in infants with neutropenia or primary or secondary immunodeficiency.

 

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Quality Standard

Items

Standard

Appearance

White to slight yellow crystalline powder

Identification

Complies

Specific rotation

-17°~ -21°(on anhydrous)

PH

4.0~6.0

Water

11.4~13.4%

Related substances

Impurity A0.3%

Impurity B0.3%

Max unspecified impurities0.3%

Total impurities1.0%

Residual solvents

Information

Bacterial endotoxins

0.12EU/mg

Assay

98.0~101.0%(on anhydrous)

Storage and transportation

 

Storage temperature: -20°C
Transportation conditions: Ultra-low temperature transportation

 

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product-480-328

Marketing

 

Our products are sold well in more than 60 countries and regions including North America, Western Europe, Southeast Asia, Central and South America, etc. We have established long-term and stable cooperative relations with pharmaceutical companies in Europe, the United States, Greece, Germany, Iran, Russia, South Korea, India and other country.

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product-1600-900

 

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